Reactions of keratinocytes to in vitro millimeter wave exposure.
نویسندگان
چکیده
The effects of millimeter waves (MW) on human keratinocytes were studied in vitro using the HaCaT keratinocyte cell line. MW-induced modulation of keratinocyte function was studied in proliferation, adhesion, chemotaxis, and interleukin-1beta (IL-1beta) production assays. Spontaneous proliferation, adhesion to tissue culture plate, random migration, and IL-8- and RANTES induced chemotaxis were not affected by exposure of cells to millimeter waves under the following conditions: frequency, 61.22 GHz; SAR, 770 W/kg; duration of exposure, 15-30 min. However, MW irradiation resulted in a modest but statistically significant increase in the intracellular level of IL-1beta. These data suggest that exposure of human skin (with keratinocytes being the major component of epidermis) to MW can cause activation of basal keratinocytes resulting in an elevated level of IL-1beta production.
منابع مشابه
Leukotrichia in Stable Segmental Vitiligo: Implication of an Alternate Treatment Option
132 Ann Dermatol Received December 14, 2012, Revised March 4, 2013, Accepted for publication March 22, 2013 Corresponding author: Sang Ho Oh, Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, Korea. Tel: 82-2-2228-2080, Fax: 82-2-393-9157, E-mail: [email protected] This is an Open...
متن کاملIn vitro Co-Culture of Human Skin Keratinocytes and Fibroblasts on a Biocompatible and Biodegradable Scaffold
Background: Extensive full-thickness burns require replacement of both epidermis and dermis. In designing skin replacements, the goal has been to re-create this model and make a product which has both essential components. Methods: In the present study, we developed procedures for establishing confluent, stratified layers of cultured human keratinocytes on the surface of modified collagen-chito...
متن کاملGallium Phosphide IMPATT Sources for Millimeter-Wave Applications
The potentiality of millimter-wave (mm-wave) double-drift region (DDR) impact avalanche transit time (IMPATT) diodes based on a wide bandgap (WBG) semiconductor material, Gallium Phosphide (GaP) has been explored in this paper. A non-sinusoidal voltage excited (NSVE) large-signal simulation method has been used to study the DC and high frequency characteristics of DDR GaP IMPATTs dsigned to ope...
متن کاملIsolation and in vitro cultivation of human skin Keratinocytes and preparation of epidermal sheet
متن کامل
Highly Selective Lowpass Filter with Wide Stopband in Suspended Stripline Technology for Millimeter-wave Diplexer Applications
This paper presents a low loss and high selective lowpass filter which is implemented using suspended stripline (SSL) technology. The proposed structure is comprised of a 13th order generalized Chebyshev lowpass filter which enjoys integrated waveguide-to-SSL transitions. This filter is designed and fabricated to be used as lowpass channel of a U-band diplexer employed in frontend of a U-band d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Bioelectromagnetics
دوره 22 5 شماره
صفحات -
تاریخ انتشار 2001